Special Price $54.95

Diabetics & Sensitive Skin

$284.40 /72 Pedipods per box
$3.95 / 1 pedipack



Stimulates healing and blood cỉculation while alleviating inflammation associated with sensitive skin with FDA approved OTC Le"K Essential Dm. This pedi-pod contains all natural ingredients such as arnica, rosemany, greem tea, grape-seed extract, vitamin E, and benzalkonium chloride that act as soothing agents and have the ability to prevent COVID-19 for up to four hours after application.

  • Peppermint Salt Soak
  • Greem Tea Walnut Scrub 
  • Mint/Eucalyptus Cooling Menthol Mask
  • Greem Tea Healing Lotion

According to the Centers for Disease Control, an estimated 37.3 million Americans have diabetes, that’s about 11.3% of the entire population. On top of that, another 96 million adults have prediabetes, making this one of the single most damaging and prevalent diseases in the United States (1). Unfortunately, the health issues related to diabetes are physiologically widespread, affecting multiple organ systems. This results in an array of uncomfortable and hard-to-treat symptoms that researchers at HCD AntiAging Laboratories are working diligently to relieve. The Essential-Dm Mani/PediPod manicure/pedicure formula, with ingredients supported by research, is one treatment they have provided, specifically to support skin ailments caused by diabetes.

Epidemiologic research has shown that in a whopping 79.2% of individuals with diabetes, skin conditions will be present. This includes an array of microbial skin infections and inflammatory skin diseases, as well as chronically dry skin, all of which can result in uncomfortable and hard to treat symptoms (2). Because diabetes is so hard to treat with success, finding alternative ways to prevent and support these presentations can be essential to maintaining the quality of life.

The Essential-Dm Mani/PediPod contains ingredients to nourish and protect the skin with the goal of soothing current issues while preventing future problems. By combining medical philosophies from both eastern and western traditions, it has been designed to include green tea extracts, grape seed extract, rosemary, arnica, vitamin E, and benzalkonium chloride, all of which contain anti-inflammatory and/or antimicrobial properties.

A concern with diabetic patients is that when blood sugars are uncontrolled long-term, peripheral circulation is reduced, and therefore so is the ability of the skin to heal - in some cases, this can be so severe, that patients can lose the limb. Green tea, containing a high relative content of an active polyphenol known as epigallocatechin gallate, or EGCG, is one medicinal herb that can combat some of these skin concerns, specifically by supporting wound healing. Though the specific mechanisms are quite complex, ECGC has been found to have antioxidant, anti-inflammatory, antimicrobial, angiogenic, and antifibrotic properties, which benefit all stages of wound healing (homeostasis, inflammation, proliferation, and remodeling). (3)

A 2019 animal study looked a little closer. They referenced the knowledge that in mice with diabetes, the persistent inflammation in the later stages of wound repair is specifically what delays healing. They found that ECGC, the active constituent in green tea, was able to inhibit the accumulation of white blood cells, the inflammatory cascade, and a specific signaling pathway known as Notch-1. Therefore, they concluded that EGCG was a novel potential medicine to treat chronic wounds, especially in diabetic patients. (4)

Grape seed extract, another ingredient of the Essential-Dm Mani/PediPod formula, is also supported in the literature as a treatment for wound healing and other diabetic complications. Though it is usually thought of as an oral supplement, a 2014 study by Hemmati et al, showed it’s potential benefit Essential-Dm TransformSalonLuxe @TransformSalonLuxe @TSLuxe 1300 1st St Suite 368, Napa, CA 94559 (916) 221-1156 | when applied topically. These researchers performed surgery on small skin lesions, with the study group receiving 2% grape seed extract cream and the controls receiving a placebo. After monitoring the healing process for 21 days, they found that the treatment group had complete repair of wounds by day 8, compared to day 14 in the control group, which was statistically significant. They attributed this success to the ability of the grape seed extract to release endothelial growth factors, therefore closing the wound and improving circulation, as well as its ability as an antioxidant and antibacterial, reducing inflammation and the risk of infection. (5) In diabetics, where wounds go unnoticed and healing times are extended, this could be a novel way to prevent complications.

Though rosemary is also known to improve wound healing, it has a bit more of a broader spectrum when it comes to its actions on skin health. The ability of its active constituents to act topically as an antioxidant and antiinflammatory has made it a commonly used herbal medicine both in the pharmaceutical and cosmetic industries. For example, carnosic acid, one of the active molecules in rosemary, was found to act as an anti-inflammatory, specifically by mediating microcirculation – pharmaceutically, this would improve healing and skin health; cosmetically, it would reduce redness, swelling, and signs of aging. A comprehensive review of potential topical applications also cited studies touting rosemary as an anti-fungal, a protectant against UV damage, adjunctive treatment for skin cancers, a possible treatment to improve the appearance of cellulite, and a possible promoter of hair growth in individuals with alopecia. (6) All these potential benefits is what led it to be added to the Essential-Dm Mani/PediPod formula.

The last herb included in the formula is colloquially known as Arnica. Though most commonly thought of as a strictly musculoskeletal herb, the actual mechanisms behind why it works for strains, sprains, and bruising may indicate significant implications on skin health. Much of arnica's success in studies is attributed to its strong antioxidant activity, with one study finding that at concentrations up to 100 mg/L, it possessed a significant protective effect against hydrogen peroxide-induced oxidative stress (inflammation), especially in skin cells. (7) In the skin of diabetics, an imbalance of free radicals and antioxidants within the skin cells causes tissue damage and delayed wound healing. (8) Therefore, supplying the strong antioxidants from arnica to the skin causes an overall improvement in tissue health, hydrating, protecting, and repairing the skin.

Herbs aren’t the only remedies that are in the Essential-Dm Mani/PediPod, however. Vitamin E, a fat-soluble vitamin known for its significant health effects, has also been included. Like many of the herbs, much of vitamin E’s popularity in dermatology and cosmetics is attributed to its antioxidant properties. However, it also has the ability to moderate the biosynthesis of collagen and glycosaminoglycans in the skin. Therefore, on top of supporting wound healing, reducing inflammation, and hydrating the skin, it also supports the integrity and strength of the skin itself. (9) This could prevent known diabetic complications such as infection or ulcer formation. In addition to these topical effects, vitamin E has shown to have neuroprotective and cardioprotective effects when taken orally. Both circulatory and nerve conduction issues occur in diabetics, especially when blood sugars are poorly controlled. Theoretically, topical application of vitamin E could benefit superficial nerves and microvasculature, improving outcomes with diabetics experiencing complications. (10)

These natural compounds are combined with benzalkonium chloride, a potent FDA-approved antimicrobial that is known to be minimally irritating to the skin. Researchers have worked diligently to combine traditional medicinal philosophies with modern medicine, providing a new, novel way to support patients suffering from various skin conditions. The Essential-Dm Mani/PediPod formula, containing green tea extracts, grape seed extract, rosemary, arnica, and vitamin E, truly combines beauty with health, specifically formulated with diabetic patients in mind, preventing and aiming to heal painful, often debilitating symptoms.